Tuesday, October 6, 2026

Africa bears 25% of global disease burden yet contributes under 4% to clinical trials, AKUH warns

By Our Staff Reporter

Health sector leaders from the Aga Khan University Hospital (AKUH), Nairobi, have issued a stark warning regarding Africa’s heavy reliance on external health expertise and research, cautioning that the status quo places the continent at severe risk.

Speaking at a high-level media briefing in Addis Ababa, AKUH Chief Executive Officer Rashid Khalani and Head of Communications Antony Kargiri highlighted a profound systemic gap in local scientific infrastructure. While Africa shoulders 25% of the global disease burden and accounts for 17% of the world’s population, it contributes less than 4% to worldwide clinical trials and remains vastly underrepresented in genomic data and medical innovation.

The officials emphasized that critical deficits in domestic research, local manufacturing, and human resource development undermine Africa’s health sovereignty. This vulnerability was laid bare during the COVID-19 pandemic.

“We have a massive population, but when the COVID pandemic hit and AstraZeneca, Moderna, and Pfizer rolled out their vaccines, we were begging, asking when the vaccines would come to us,” Khalani stated.

He noted that insufficient investment in local research leaves the continent similarly exposed regarding other essential vaccines and therapeutics. Furthermore, continental healthcare financing continues to lag significantly behind regional targets. Although African nations pledged under the Abuja Declaration to allocate at least 15% of national budgets to health, actual domestic expenditure in most countries remains below 5%, stifling infrastructure development, pharmaceutical manufacturing, and specialized training.

To combat these systemic hurdles, AKUH has pioneered targeted interventions, including a dedicated clinical research center in Nairobi that has completed 18 studies, trained 150 investigators, and enrolled hundreds of participants. However, executives stressed that domestic research centers cannot operate in isolation. Sustainable growth demands robust South-South partnerships, increased domestic investment, and clinical research tailored specifically to Africa’s unique disease burdens.

As part of its broader regional strategy, AKUH signaled a strong intent to expand its cooperative footprint in Ethiopia. Khalani announced ongoing engagements with Ethiopian universities and health institutions to forge agreements focused on professional training, knowledge exchange, and joint research. Additionally, AKUH is streamlining affordable healthcare packages and travel logistics for Ethiopian patients traveling to its Nairobi facility, aided by Ethiopian Airlines’ robust transit network.

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